Do kids have a natural immunity to fifth disease once they've had the virus?
– Lenore

Fifth disease is one of the most common and contagious childhood illnesses. Fortunately, fifth disease doesn't tend to make a child very ill. A "slapped-cheek" rash on the face that spreads to the body and mild, cold-like symptoms (like a low-grade fever and runny nose) are usually the only symptoms.

One good thing about fifth disease is that kids who've been infected with the virus that causes it (parvovirus B29) become immune to it and won't usually become infected again.

For more information, check out these articles:
Fifth Disease
Birth Defects

Reviewed by: Larissa Hirsch, MD
Date reviewed: October 2006

Have a question? Email us.

Although we can't reply personally, you may see your question posted to this page in the future. If you're looking for medical advice, a diagnosis, or treatment, consult your doctor or other qualified medical professional. If this is an emergency, contact emergency services in your area.